The antiphospholipid syndrome and heart valve surgery
نویسندگان
چکیده
منابع مشابه
The antiphospholipid syndrome and heart valve surgery.
The antiphospholipid syndrome (APLS) is a complex autoimmune disease often connected to systemic lupus erythematodes. Main features are thromboses, fetal loss and specific antibodies. The involved autoantibodies are directed against plasma proteins such as beta2glycoprotein1 (beta2GPI) or prothrombin which depend on negatively charged phospholipids. Direct antibodies against phospholipids are o...
متن کاملHeart valve surgery in patients with the antiphospholipid syndrome: analysis of a series of nine cases.
OBJECTIVE Antiphospholipid syndrome (APS) is a rare coagulation disorder associated with recurrent arterial and venous thrombotic events. Heart valve abnormalities are commonly found in patients with APS. METHODS From March 1998 to March 2007, nine patients with APS underwent heart valve surgery using cardiopulmonary bypass. We retrospectively reviewed their clinical data, operative and posto...
متن کاملANTIPHOSPHOLIPID ANTIBODY SYNDROME-A CASE OF AORTIC VALVE INSUFFICIENCY
A 31 year old woman was hospitalized for evaluation of aortic valve insufficiency and her present cardiac status. Clinical and paraclinical findings strongly suggested the presence of a collagen vascular inflammatory processprecisely, the antiphospholipid antibody syndrome (APS), with systemic lupus erythematosus as the underlying disease.
متن کاملCardiac valve diseases and antiphospholipid syndrome.
Antiphospholipid syndrome (APS) has been recognized as one of the most commontypes of thrombophilia (1). Its main clinical features are arterial/venous thrombosis and pregnancy loss associated with placenta thrombosis. However, other heterogeneous clinical manifestations may be associated with APS, such as thrombocytopenia, haemolytic anemia, neurological impairment and pulmonary hypertension (...
متن کاملAntiphospholipid syndrome, cardiac surgery and cardiopulmonary bypass.
of APLS are cerebrovascular accident, transient ischemic attack, seizures, chorea, migraine, pseudotumor cerebri, visual disturbances and dementia. Cutaneous features include livedo reticularis, ulcers, infarcts and superficial thrombophlebitis. These patients may develop renal arterial or venous thrombosis, acute or chronic renal failure, hemolytic anemia or thrombocytopenia.[15-17] Catastroph...
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ژورنال
عنوان ژورنال: European Journal of Cardio-Thoracic Surgery
سال: 2008
ISSN: 1010-7940
DOI: 10.1016/j.ejcts.2007.11.004